Dele Alli and Hugo Lloris have both been ruled out of Tottenham’s game with Liverpool on Saturday due to injury.
Lloris, who was sentenced for a drink-driving charge on Wednesday, will be missing for several weeks with a thigh injury.
He picked up the problem during their 3-0 win over Manchester United in August.
Alli misses out having picked up a hamstring injury, while on international duty with England.
The match is scheduled for 12.45 on Saturday at Wembley Stadium.
Liverpool are on top with 12 points, while Spurs are in fifth place with 9 points.